Neurological and Psychiatric disorders pose a major socioeconomic burden. Our goal is to determine how genetic mutations underlie the pathobiology of nervous system disorders. We take advantage of cutting edge genomic technologies to study the human brain at unprecendented resolution. We specifically seek to :

1. Identify molecular programs regulating cell type distinctions in the human nervous system, and to identify changes in disease;

2. Uncover the regulatory networks that control stem cell differentiation that could be utilized to increase the precision and safety of stem cell - based therapies;

 3. Develop new experimentally tractable model of human disease that enable interrogation of disease mechanisms and discovery of new therapeutic opportunities.

Cross-disciplinary Research

We are excited to actively participate in the following consortia efforts:

Pediatric Networks for the Human Cell Atlas

Funding sources

We are grateful for the generous support of our sponsors:

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